Abstract: New mono acid esters have been synthesized from the reaction of benzoic acid and mono-hydroxybenzoic acids with 2-phenoxyethanol separated from Urtica pilulifera, characterized, and screened for possible antioxidant, antifungal, antimicrobial and anticancer activities. 2-phenoxyethyl 4-hydroxy benzoate showed considerable activity against MCF-7 with IC50 is less than 62.5 µg/ml, and complete inhibition at a concentration less than 37.5 µg/ml against M. canis and less than 50 µg/ml against T. rubrum. On the other hand 2-phenoxyethyl 2-hydroxy benzoate reveals 70% of gentamicin against K. pneumoniae. Key words: Hydroxybenzoic acids, benzoic acid, 2-phenoxyethanol, antioxidant, antibacterial, antifungal, anticancer.
Iranian Journal of Pharmaceutical Research (IJPR)
Hydroxybenzoic acids, 2-phenoxyethanol, Antioxidant, Antimicrobial, Anticancer